|
Substrates (trade name)
|
Inhibitors (trade name)
|
Inducers (trade name)
|
|
CYP1A2
|
|
|
|
Alosetron (Lotronex)
Amitriptyline (Elavil)
Anagrelide (Agrylin)
Aprepitant (Emend)
Caffeine
Cinacalcet (Sensipar)
Clomipramine (Anafranil)
Clozapine (Clozaril)
Cyclobenzaprine (Flexeril)
Desipramine (Norpramin)
Diazepam (Valium)
Diphenhydramine (Benadryl)
Duloxetine (Cymbalta)
Erlotinib (Tarceva)
Flutamide (Eulexin)
Fluvoxamine (Luvox)
Frovatriptan (Frova)
Gingko
Haloperidol (Haldol)
Imipramine (Tofranil)
Indiplon
Lidocaine
Melatonin
Mexiletine (Mexitil)
Mirtazapine (Remeron)
Olanzapine (Zyprexa)
Ondansetron (Zofran)
Palonosetron (Aloxi)
Pimozide (Orap)
Propranolol (Inderal)
Ramelteon (Rozerem)
Rasagiline (Azilect)
Ropinirole (Requip)
Ropivacaine (Naropin)
R-warfarin (Coumadin)
Selegiline (Eldepryl)
Tacrine (Cognex)
Tamoxifen (Nolvadex)
Theophylline, aminophylline (Aerolate, Aquaphyllin, Asmalix, Bronkodyl, Choledyl, Constant-T, Duraphyl, Elixophyllin, Phyllocontin, Quibron, Respbid, Slo-bid, Slo-Phyllin, Sustaire, Theo-24, Theobid, Theochron, Theoclear, Theo-Dur, Theolair, Theon, Theospan, Theovent, Truphylline)
Thiabendazole (Mintezol)
Tizanidine (Zanaflex)
Triamterene
Zafirlukast (Accolate)
Zileuton (Zyflo)
Zolmitriptan (Zomig)
|
Artemisinin
Atazanavir (Reyataz)
Cimetidine (Tagamet)
Ciprofloxacin (Cipro)
Clarithromycin (Biaxin)
Enoxacin (Penetrex)
Erythromycin (E-Mycin)
Ethinyl estradiol
Fluvoxamine (Luvox)
Grapefruit juice
Isoniazid (INH, Nydrazid)
Ketoconazole (Nizoral)
Mexiletine (Mexitil)
Norfloxacin (Chibroxin, Noroxin, Norflox)
Tacrine (Cognex)
Thiabendazole (Mintezol)
Zafirlukast (Accolate)
Zileuton (Zyflo)
|
Cigarette smoke
Phenobarbital (Luminal)
Rifampin (Rifadin, Rimactane)
Ritonavir (Norvir)
|
|
CYP2C9
|
|
|
|
Alosetron (Lotronex)
Amprenavir (Agenerase)
Azapropazone
Bosentan (Tracleer)
Candesartan (Atacand)
Celecoxib (Celebrex)
Chlorpropamide (Diabinese)
Diclofenac (Cataflam, Voltaren)
Doxepin (Sinequan)
Dronabinol (Marinol)
Fluoxetine (Prozac)
Flurbiprofen (Ansaid)
Fluvastatin (Lescol)
Glimepiride (Amaryl)
Glipizide (Glucotrol)
Glyburide (DiaBeta)
Ibuprofen (Advil, Motrin)
Indomethacin (Indocin)
Irbesartan (Avapro)
Losartan (Cozaar)
Melatonin
Meloxicam (Mobic)
Montelukast (Singulair)
Naproxen (Aleve, Naprosyn)
Nateglinide (Starlix)
Phenytoin (Dilantin)
Piroxicam (Feldene)
Ramelteon (Rozerem)
Rosiglitazone (Avandia)
Rosuvastatin (Crestor)
Sildenafil (Viagra)
Sitaxsentan
Sulfamethoxazole (Bactrim, Gantanol, Septra, Sulfatrim)
S-warfarin (Coumadin)
Tolbutamide (Orinase)
Torsemide (Demadex)
Valdecoxib (Bextra)
Valsartan (Diovan)
Voriconazole (Vfend)
|
Alcohol (intoxicating dose)
Amiodarone (Cordarone, Pacerone)
Benzbromarone
Cimetidine (Tagamet)
Clopidogrel (Plavix)
Delavirdine (Rescriptor)
Disulfiram (Antabuse)
Doxifluridine
Efavirenz (Sustiva)
Fluconazole (Diflucan)
Fluorouracil (5-FU)
Fluoxetine (Prozac)
Fluvastatin (Lescol)
Fluvoxamine (Luvox)
Gemfibrozil (Lopid)
Imatinib (Gleevec)
Isoniazid (INH, Nydrazid)
Leflunomide (Arava)
Metronidazole (Flagyl)
Miconazole (Monistat)
Modafinil (Provigil)
Phenytoin (Dilantin)
Sertraline (Zoloft)
Sitaxsentan
Sulfamethoxazole (Bactrim, Gantanol, Septra, Sulfatrim)
Sulfaphenazole
Sulfinpyrazone (Anturane)
Trimethoprim (Bactrim, Primsol, Proloprim, Septra, Sulfatrim, Trimpex)
Valproic Acid (Depakene)
Voriconazole (Vfend)
Zafirlukast (Accolate)
|
Aminoglutethimide (Cytadren)
Aprepitant (Emend)
Barbiturates
Bosentan (Tracleer)
Carbamazepine (Tegretol)
Phenobarbital (Luminal)
Rifampin (Rifadin, Rimactane)
|
|
CYP2C19
|
|
|
|
Aprepitant (Emend)
Aripiprazole (Abilify)
Carisoprodol (Soma)
Citalopram (Celexa)
Clomipramine (Anafranil)
Clopidogrel (Plavix)
Clozapine (Clozaril)
Desipramine (Norpramin)
Diazepam (Valium)
Diphenhydramine (Benadryl)
Doxepin (Sinequan)
Escitalopram (Lexapro)
Flunitrazepam
Fluoxetine (Prozac)
Imipramine (Tofranil)
Lansoprazole (Prevacid)
Mephenytoin (Mesantoin)
Methadone
Moclobemide (Manerix)
Nelfinavir (Viracept)
Olanzapine (Zyprexa)
Omeprazole (Prilosec)
Pantoprazole (Protonix)
Pentamidine (Pentam)
Phenobarbital
Phenytoin (Dilantin)
Proguanil (active metabolite)
Propranolol (Inderal)
Rabeprazole (Aciphex)
R-warfarin (Coumadin)
Sertraline (Zoloft)
Thalidomide (Thalomid)
Voriconazole (Vfend)
|
Chloramphenicol
Cimetidine (Tagamet)
Clopidogrel (Plavix)
Delavirdine (Rescriptor)
Efavirenz (Sustiva)
Felbamate (Felbatol)
Fluconazole (Diflucan)
Fluoxetine (Prozac)
Fluvastatin (Lescol)
Fluvoxamine (Luvox)
Isoniazid (INH, Nydrazid)
Ketoconazole (Nizoral)
Lansoprazole (Prevacid)
Moclobemide (Manerix)
Modafinil (Provigil)
Omeprazole (Prilosec)
Oxcarbazepine (Trileptal)
Ticlopidine (Ticlid)
Topiramate (Topamax)
Voriconazole (Vfend)
|
Artemisinin
Barbiturates
Carbamazepine (Tegretol)
Phenytoin (Dilantin)
Norethindrone
Rifampin (Ramactane)
St. John's wort
|
|
CYP2D6
|
|
|
|
Almotriptan (Axert)
Alprenolol
Amitriptyline (Elavil)
Amprenavir (Agenerase)
Atomoxetine (Strattera)
Bisoprolol (Zebeta)
Carvedilol (Coreg)
Cevimeline (Evoxac)
Chlorpheniramine
Chlorpromazine (Thorazine)
Cinacalcet (Sensipar)
Citalopram (Celexa)
Clomipramine (Anafranil)
Codeine
Cyclobenzaprine (Flexeril)
Darifenacin (Enablex)
Debrisoquin
Desipramine (Norpramin)
Dextromethorphan
Dihydrocodeine
Diphenhydramine (Benadryl)
Dolasetron (Anzemet)
Donepezil (Aricept)
Doxepin (Sinequan)
Duloxetine (Cymbalta)
Encainide
Escitalopram (Lexapro)
Flecainide (Tambocor)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Galantamine (Reminyl)
Haloperidol (Haldol)
Hydrocodone
Imipramine (Tofranil)
Loratadine (Claritin)
Maprotiline (Ludiomil)
Methadone
Methamphetamine
Metoclopramide (Reglan)
Metoprolol (Lopressor)
Mexiletine (Mexitil)
Mianserin
Mirtazapine (Remeron)
Nortriptyline (Aventyl, Pamelor)
Olanzapine (Zyprexa)
Ondansetron (Zofran)
Oxycodone (Endocodone, OxyContin, OxyIR, Percodan, Percolone, Roxicodone)
Palonosetron (Aloxi)
Paroxetine (Paxil)
Perhexiline (Pexid)
Perphenazine (Trilafon)
Promethazine (Phenergan)
Propafenone (Rhythmol)
Propoxyphene (Darvon)
Propranolol (Inderal)
Protriptyline (Vivactil)
Ranolazine (Ranexa)
Risperidone (Risperdal)
Sertindole (Serlect)
Sertraline (Zoloft)
Simvastatin (Zocor)
Tamoxifen (Nolvadex)
Thioridazine (Mellaril)
Timolol (Betimol, Blocadren, Timoptic)
Tolterodine (Detrol)
Tramadol (Ultram)
Trazodone (Desyrel)
Venlafaxine (Effexor)
Yohimbine
|
Amiodarone (Cordarone, Pacerone)
Bupropion (Wellbutrin)
Chloroquine (Aralen)
Chlorpheniramine
Chlorpromazine (Thorazine)
Celecoxib (Celebrex)
Cimetidine (Tagamet)
Cinacalcet (Sensipar)
Citalopram (Celexa)
Clomipramine (Anafranil)
Diphenhydramine (Benadryl)
Duloxetine (Cymbalta)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Halofantrine (Halfan)
Haloperidol (Haldol)
Hydroxychloroquine
Imatinib (Gleevec)
Paroxetine (Paxil)
Perphenazine (Trilafon)
Promethazine (Phenergan)
Propafenone (Rhythmol)
Propoxyphene (Darvon)
Quinacrine
Quinidine (Cardioquin, Dura-Tabs, Quinaglute, Quinidex)
Quinine
Ranolazine (Ranexa)
Risperidone (Risperdal)
Ritonavir (Norvir)
Sertraline (Zoloft)
Terbinafine (Lamisil)
Thioridazine (Mellaril)
|
Rifampin (Rifadin, Rimactane)
|
|
CYP2E1
|
|
|
|
Acetaminophen (Tylenol)
Chlorzoxazone (Parafon Forte)
Ethanol, enflurane, halothane, isoflurane, methoxyflurane, sevoflurane
Theophylline, aminophylline (Aerolate, Aquaphyllin, Asmalix, Bronkodyl, Choledyl, Constant-T, Duraphyl, Elixophyllin, Phyllocontin, Quibron, Respbid, Slo-bid, Slo-Phyllin, Sustaire, Theo-24, Theobid, Theochron, Theoclear, Theo-Dur, Theolair, Theon, Theospan, Theovent, Truphylline)
|
Disulfiram (Antabuse)
|
Chronic ethanol Isoniazid (INH, Nydrazid)
|
|
CYP3A
|
|
|
|
Alfentanil (Alfenta)
Alfuzosin (Uroxatral)
Almotriptan (Axert)
Alosetron (Lotronex)
Alprazolam (Xanax)
Amiodarone (Cordarone)
Amitriptyline (Elavil)
Amlodipine (Norvasc)
Amprenavir (Agenerase)
Aprepitant (Emend)
Aripiprazole (Abilify)
Astemizole (Hismanal)
Atazanavir (Reyataz)
Atorvastatin (Lipitor)
Bepridil (Vascor)
Bexarotene (Targretin)
Bosentan (Tracleer)
Bromocriptine (Parlodel)
Budesonide (Entocort)
Bupivacaine (Sensorcaine)
Buprenorphine (Subutex)
Buspirone (Buspar)
Calcium channel blockers
Carbamazepine (Tegretol)
Cevimeline (Evoxac)
Chlorpheniramine
Cilostazol (Pletal)
Cinacalcet (Sensipar)
Cisapride (Propulsid)
Citalopram (Celexa)
Clarithromycin (Biaxin)
Clomipramine (Anafranil)
Clonazepam (Klonopin)
Clopidogrel (Plavix)
Clozapine (Clozaril)
Colchicine
Conivaptan (Vaprisol)
Cyclobenzaprine (Flexeril)
Cyclophosphamide (Cytoxan)
Cyclosporine (Gengraf, Neoral, Sandimmune)
Dapsone (Avlosulfon)
Darifenacin (Enablex)
Darunavir (Prezista)
Dasatinib (Sprycel)
Delavirdine (Rescriptor)
Dexamethasone (Decadron)
Dextromethorphan
Diazepam (Valium)
Diclofenac (Voltaren)
Dihydroergotamine (D.H.E. 45)
Diltiazem (Cardizem)
Disopyramide (Norpace)
Docetaxel (Taxotere)
Dolasetron (Anzemet)
Donepezil (Aricept)
Doxorubicin (Adriamycin)
Droperidol
Dutasteride (Avodart)
Ebastine (Kestine)
Efavirenz (Sustiva)
Eletriptan (Relpax)
Eplerenone (Inspra)
Ergotamine (Ergomar)
Erlotinib (Tarceva)
Erythromycin (E-Mycin)
Escitalopram (Lexapro)
Estazolam (Prosom)
Estrogens
Eszopiclone (Lunesta)
Ethosuximide (Zarontin)
Etoposide (Vepesid)
Exemestane (Aromasin)
Felodipine (Plendil)
Fentanyl (Sublimaze)
Finasteride (Proscar)
Flunitrazepam
Flurazepam (Dalmane)
Fosamprenavir (Lexiva)
Galantamine (Reminyl)
Garlic
Gefitinib (Iressa)
Gingko
Granisetron (Kytril)
Halofantrine (Halfan)
Haloperidol (Haldol)
Ifosfamide (Ifex)
Imatinib (Gleevec)
Imipramine (Tofranil)
Indiplon
Irinotecan (Camptosar)
Isradipine (DynaCirc)
Itraconazole (Sporanox)
Ivabradine
Ixabepilone (Ixempra)
Ketoconazole (Nizoral)
Lansoprazole (Prevacid)
Lapatinib (Tykerb)
Levomethadyl (Orlaam)
Lidocaine
Loperamide (Imodium)
Loratadine (Claritin)
Losartan (Cozaar)
Lovastatin (Mevacor)
Maraviroc (Selzentry)
Mefloquine (Lariam)
Meloxicam (Mobic)
Methadone
Methylprednisolone
Midazolam (Versed)
Mifepristone (Mifeprex)
Mirtazapine (Remeron)
Modafinil (Provigil)
Montelukast (Singulair)
Nateglinide (Starlix)
Nefazodone (Serzone)
Nicardipine (Cardene)
Nifedipine (Adalat)
Nimodipine (Nimotop)
Nisoldipine (Sular)
Nitrendipine (Baypress)
Omeprazole (Prilosec)
Ondansetron (Zofran)
Oxybutynin (Ditropan)
Oxycodone (Percodan)
|
Amiodarone (Cordarone, Pacerone)
Amprenavir (Agenerase)
Aprepitant (Emend)
Aripiprazole (Abilify)
Atazanavir (Reyataz)
Chloramphenicol
Cimetidine (Tagamet)
Clarithromycin (Biaxin)
Conivaptan (Vaprisol)
Cyclosporine (Neoral)
Danazol (Danocrine)
Darunavir (Prezista)
Dasatinib (Sprycel)
Delavirdine (Rescriptor)
Diltiazem (Cardizem)
Erythromycin (E-Mycin)
Estrogens
Fluconazole (Diflucan)
Fluoxetine (Prozac)
Fluvoxamine (Luvox)
Fosamprenavir (Lexiva)
Grapefruit juice
Imatinib (Gleevec)
Indinavir (Crixivan)
Interleukin-10
Isoniazid (INH, Nydrazid)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Lapatinib (Tykerb)
Miconazole (Monistat)
Mifepristone (Mifeprex)
Nefazodone (Serzone)
Nelfinavir (Viracept)
Nicardipine (Cardene)
Norfloxacin (Chibroxin, Noroxin)
Posaconazole (Noxafil)
Propoxyphene (Darvon)
Quinupristin (Synercid)
Ranolazine (Ranexa)
Ritonavir (Norvir)
Saquinavir (Fortovase, Invirase)
Tamoxifen (Nolvadex)
Telithromycin (Ketek)
Troleandomycin (TAO)
Verapamil (Calan)
Voriconazole (Vfend)
Zafirlukast (Accolate)
|
Aminoglutethimide (Cytadren)
Barbiturates
Bexarotene (Targretin)
Bosentan (Tracleer)
Carbamazepine (Tegretol)
Dexamethasone (Decadron)
Efavirenz (Sustiva)
Glucocorticoids
Griseofulvin (Grisactin)
Modafinil (Provigil)
Nafcillin (Unipen)
Nevirapine (Viramune)
Oxcarbazepine (Trileptal)
Phenobarbital (Luminal)
Phenytoin (Dilantin)
Primidone (Mysoline)
Rifabutin (Mycobutin)
Rifampin (Rifadin, Rimactane)
St. John's wort
Topiramate (Topamax)
|
|
Paclitaxel (Taxol)
Palonosetron (Aloxi)
Pantoprazole (Protonix)
Paricalcitol (Zemplar)
Pimozide (Orap)
Pioglitazone (Actos)
Praziquantel (Biltricide)
Prednisolone
Prednisone
Propoxyphene (Darvon)
Protease inhibitors
Quazepam (Doral)
Quetiapine (Seroquel)
Quinacrine
Quinidine (Cardioquin, Quinaglute, Quinidex)
Quinine
Ramelteon (Rozerem)
Ranolazine (Ranexa)
Repaglinide (Prandin)
Rifabutin (Mycobutin)
Risperidone (Risperdal)
Ritonavir (Norvir)
Ropivacaine (Naropin)
R-warfarin (Coumadin)
Selegiline (Eldepryl)
Sertindole (Serlect)
Sertraline (Zoloft)
Sibutramine (Meridia)
Sildenafil (Viagra)
Simvastatin (Zocor)
Sirolimus (Rapammune)
Sitaxsentan
|
|
|
|
Solifenacin (Vesicare)
Sufentanil (Sufenta)
Sulfamethoxazole (Bactrim)
Sunitinib (Sutent)
Tacrolimus (Prograf)
Tadalafil (Cialis)
Tamoxifen (Nolvadex)
Tamsulosin (Flomax)
Teniposide (Vumon)
Terfenadine
Testosterone
Theophylline
Tiagabine (Gabitril)
Tinidazole (Tindamax)
Tipranavir (Aptivus)
Tolterodine (Detrol)
Topiramate (Topamax)
Tramadol (Ultram)
Trazodone (Desyrel)
Triamterene
Triazolam (Halcion)
Valdecoxib (Bextra)
Vardenafil (Levitra)
Venlafaxine (Effexor)
Verapamil (Calan)
Vesnarinone
Vinblastine (Velbane)
Vincristine (Oncovin)
Voriconazole (Vfend)
Yohimbine
Ziprasidone (Geodon)
Zolpidem (Ambien)
Zonisamide (Zonegran)
Zopiclone (Imovane)
|
|
|
