Operative Techniques in Orthopaedic Surgery (4 Volume Set) 1st Edition

498. Osteochondral Transfer for Osteochondral Lesions of the Talus

Mark E. Easley and Justin Orr

DEFINITION

images Medium-sized osteochondral defects of the talar dome

images May approach the talar shoulder (transition of superior dome cartilage to the medial or lateral talar cartilage)

images Often associated with subchondral cysts

images Osteochondral defect is reconstructed with a cylindrical osteochondral graft. To provide stability to this graft, the osteochondral defect in the native talus must be contained (have circumferential cartilage and subchondral bone).

ANATOMY

images Sixty percent of the talus' surface area is covered by articular cartilage.

images The talus is contained within the ankle mortise.

images Superior talar dome articulates with the tibial plafond.

images Medial dome articulates with the medial malleolus.

images Lateral dome articulates with the lateral malleolus.

images Talar blood supply

images Posterior tibial artery

images Artery of the tarsal canal

images Deltoid ligament branch

images Peroneal artery

images Artery of the tarsal sinus

images Dorsalis pedis artery

PATHOGENESIS

images The pathogenesis for osteochondral lesions of the talus (OLTs) is not fully understood.

images Theories include:

images Trauma

images Idiopathic focal avascular necrosis

NATURAL HISTORY

images In general, OLTs do not progress to diffuse ankle arthritis.

images However, large-volume OLTs may lead to subchondral collapse of a substantial portion of the talus and thus create deformity, higher contact stresses, and a greater concern for eventual ankle arthritis if left untreated.

PATIENT HISTORY AND PHYSICAL FINDINGS

images Patients may or may not report a history of trauma.

images Ankle pain, typically on the anterior aspect of the ankle, is a common complaint.

images Pain is usually experienced on the side of the ankle that corresponds with the OLT, but it may be poorly localized to the site of the OLT. In fact, sometimes medial OLTs produce lateral ankle pain and vice versa.

images Pain is rarely sharp, unless a fragment of the OLT should act as an impinging loose body in the joint.

images Typically the pain is a deep ache, with and after activity, and is usually relieved with rest.

images Antalgic gait

images May be associated with malalignment or ankle instability

images Typically tenderness on side of ankle that corresponds with OLT, but not always

images Rarely crepitance or mechanical symptoms

images With chronic OLT, some degree of ankle stiffness is anticipated.

IMAGING AND OTHER DIAGNOSTIC STUDIES

images Plain radiographs

images Obtain weight-bearing, three views of the ankle

images Small OLTs may be missed.

images Large OLTs are usually identified on plain radiographs (FIG 1).

images Often limited in characterizing OLT since the twodimensional study cannot define the three-dimensional OLT

images Particularly useful in assessing lower leg, ankle, or foot malalignment that needs to be considered in the management of OLTs

images May detect incidental OLTs (patient has a radiograph for a different problem and an OLT is incidentally identified on plain radiographs)

images MRI

images Excellent screening tool when OLT or other foot–ankle pathology is suspected

images Will identify incidental OLT, but defines other potential soft tissue pathology

images Demonstrates associated marrow edema that may lead to overestimation of the OLT's size

images CT (FIG 2)

images Ideal for characterizing OLT, particularly large-volume defects

images Defines OLT size without distraction of associated marrow edema

images Defines the character of the OLT and extent of its involvement in the talar dome

images Diagnostic injection

images Intra-articular

images An anesthetic versus anesthetic plus corticosteroid

images May have some therapeutic effect, even for several months

images If the source of pain is the OLT, then intra-articular injection should relieve symptoms from OLT. If the pain is not relieved, then other diagnoses should be considered.

DIFFERENTIAL DIAGNOSIS

images Loose body in ankle joint

images Ankle impingement (anterior or posterior)

images Chronic ankle instability (medial, lateral, or syndesmotic)

images

FIG 1 • Radiographs. A. AP radiograph of the ankle suggests symmetric alignment and a medial talar dome defect. B. Mortise view also suggests medial osteochondral lesion of the talus. C. Lateral view shows anatomic alignment, with osteochondral lesion of the talus less obvious.

images Ankle synovitis or adjacent tendinopathy

images Early ankle degenerative change

NONOPERATIVE MANAGEMENT

images Activity modification

images Bracing

images Physical therapy if associated ankle instability

images Nonsteroidal anti-inflammatories or COX-2 inhibitors

images Corticosteroid injection

images Viscosupplementation?

SURGICAL MANAGEMENT

Preoperative Planning

images Indications for this surgery include:

images Medium-sized OLTs not amenable to other joint-sparing procedures. If associated with a large subchondral cyst, then arthroscopic débridement and microfracture may not be effective, and some surgeons recommend osteochondral transfer as a primary procedure.

images Failed arthroscopic (débridement and microfracture) management

images Potential sites for graft harvest

images Patient's ipsilateral knee (superolateral femoral condyle, intracondylar notch)

images Allograft talus

images Ipsilateral knee versus talar allograft

images Knee is autograft; however, knee cartilage is thicker than ankle cartilage and may have different biomechanical properties.

images Allograft talus offers nearly the same cartilage thickness and harvest from the exact location of the native talus' defect; however, it is not the patient's own tissue.

images The surgeon should check for associated pathology that may need to be addressed at the time of allograft talar reconstruction:

images Osteophyte removal

images Ligament reconstruction

images Corrective osteotomies (calcaneal, supramalleolar)

images

FIG 2 • CT. A. Coronal view with medial osteochondral lesion of the talus that approaches talar shoulder but appears contained. B. Sagittal view demonstrating rather medial osteochondral lesion of the talus. C. Axial view with posteromedial osteochondral lesion of the talus.

images Patient education

images This is a complex procedure.

images The patient must understand that the intent is to transfer cartilage and bone from one location to another and expect it to incorporate into the native talus.

images If allograft is used, there is a negligible but real risk of disease transmission and possible graft rejection by the host.

images There is no guarantee that the procedure will work, and a revision procedure may be required, such as structural allograft reconstruction or potentially ankle arthrodesis.

Positioning

images The patient is positioned supine (FIG 3).

images For a lateral OLT, a bolster under the ipsilateral hip typically affords better access to the lateral talar dome.

images We routinely use a thigh tourniquet.

Approach

images The surgeon must determine the optimal surgical approach:

images Medial talar dome (usually centromedial or posteromedial) typically warrants a medial malleolar osteotomy.

images

FIG 3 • Positioning is supine, with easy access to the medial ankle but without too much external rotation, which would make access to the lateral knee cumbersome.

images Lateral talar dome (often centrolateral) typically necessitates ligament releases (anterior talofibular and calcaneofibular) with or without lateral malleolar osteotomy.

images The key is that exposure must allow perpendicular access to the OLT; otherwise, the dedicated instrumentation for the osteochondral transfer cannot be used.

TECHNIQUES

MEDIAL APPROACH FOR A MEDIAL OSTEOCHONDRAL LESION OF THE TALUS

images Make a longitudinal incision centered over the medial malleolus (TECH FIG 1A).

images Anterior ankle arthrotomy

images Identify the joint line (TECH FIG 1B).

images Visualize the anterior talus and possibly anterior OLT (TECH FIG 1C).

images Open the flexor retinaculum (TECH FIG 1D).

images Identify and protect the posterior tibial tendon (PTT) (TECH FIG 1E).

images Predrill the intended screw holes for fixation of the osteotomy.

images Two parallel drill holes in the same orientation are typically used for open reduction and internal fixation (ORIF) of a medial malleolar fracture (TECH FIG 1F).

images Consider tapping the screw holes as well (traditional malleolar screws are not self-tapping) (TECH FIG 1G).

images Trajectory of the oblique osteotomy

images Should target tibial plafond at lateral extent of OLT

images Allows perpendicular access to the OLT with the dedicated instrumentation

images

images

TECH FIG 1A. Medial approach is similar to that for open reduction and internal fixation for a medial malleolar fracture. B, C. Anterior ankle arthrotomy. B. Locating joint and performing the medial capsulotomy. C.Medial talar dome visible through the arthrotomy with capsule retracted. This defines the anterior margin for the osteotomy. Rarely, the osteochondral lesion of the talus may be accessed via arthrotomy alone, but this is more common for lateral lesions. D, E. Defining posterior tibia for the osteotomy. D. Opening the flexor retinaculum. E. Identifying the posterior tibial tendon (to be protected during the osteotomy). F, G. Predrilling the medial malleolus. F. Drill bit directed as it would be for medial malleolar screws for open reduction and internal fixation of a medial malleolar fracture. G. Tap used for screws that are not self-tapping.

images We routinely use a Kirschner wire to determine the trajectory for the osteotomy.

images Place the wire slightly proximal and lateral to the planned osteotomy so as not to interfere with the saw blade and chisel (TECH FIG 2A).

images Confirm desired Kirschner wire trajectory with fluoroscopy.

images Mark the osteotomy.

images Across the periosteum and with minimal periosteal stripping (TECH FIG 2B)

images Perpendicular to the tibial shaft axis

images Protect the soft tissues:

images Tibialis anterior retracted

images PTT retracted. Do not mistake the flexor digitorum longus for the PTT (PTT rests in a groove directly on the posterior aspect of tibia).

images Performing the osteotomy

images Microsagittal saw (TECH FIG 2C)

images To the subchondral bone

images Use cool saline irrigation to limit risk of heat necrosis fo the bone.

images Chisel (TECH FIG 2D)

images Complete the osteotomy with a chisel.

images Periodically check the progress of the osteotomy fluoroscopically to confirm trajectory and to avoid injury to the talar dome.

images Reflect medial malleolus on the deltoid ligament (TECH FIG 2E).

images The PTT sheath must be released from the malleolus to allow full reflection of the malleolus.

Lateral Approach for a Lateral Osteochondral Lesion of the Talus

images Ideal for lateral OLT associated with lateral ankle instability

images Lateral ligaments may be released even without ligament instability.

images Make a longitudinal incision over the distal lateral fibula and curve it slightly anteriorly at the distal margin.

images Protect the sural nerve and lateral branch of the superficial peroneal nerve.

images Identify the inferior extensor retinaculum and mobilize it to be used as augmentation to lateral ligament repair at the conclusion of the cartilage procedure.

images Identify the peroneal tendons and protect them throughout the procedure.

images Release the joint capsule, with anterior talofibular and calcaneofibular ligaments, from the distal fibula.

images In many patients, plantarflexion and inversion allows sufficient anterior subluxation of the talus to perform osteochondral transfer with the dedicated instruments perpendicular to the osteochondral defect.

images If the exposure is not sufficient with soft tissue release alone, a fibular osteotomy may be performed to gain access to the more posteriorly situated lateral OLT.

images Fibular osteotomy

images We routinely perform an oblique fibular osteotomy, similar to the pattern of a Weber B ankle fracture.

images

TECH FIG 2A. Kirschner wire is used to define the trajectory of the osteotomy. So that the wire does not interfere with the saw blade, it is placed slightly more proximal and directly slightly more lateral than the intended osteotomy. B–D. Medial malleolar osteotomy. B. The periosteum is incised at the starting point, perpendicular to the longitudinal axis of the tibia (virtually no periosteal stripping required). C. Microsagittal saw is used to perform the osteotomy. Note the Kirschner wire used to guide the saw. D. A chisel is used to carefully complete the osteotomy. E. The medial malleolus is reflected, exposing the osteochondral lesion of the talus.

images When performed with the ligament release described above, exposure is markedly enhanced.

images Before performing the osteotomy, we place a small fragment plate on the lateral fibula that spans the proposed osteotomy and predrill the holes.

images With the peroneal tendons and superficial peroneal nerve protected, perform the osteotomy obliquely using a microsagittal saw.

images Cool saline irrigation to limit bony heat necrosis

images Avoid injuring intact articular cartilage on talus.

images Syndesmotic ligaments remain intact.

Osteochondral Transfer

images Single-stage operation

images Donor options:

images Autograft from ipsilateral knee

images Arthrotomy versus arthroscopic

images Superolateral femoral condyle versus intracondylar notch

images Moderate amount of donor graft available

images Autograft from ipsilateral talus

images Limited donor graft available

images Allograft talus

images Fresh allograft ideal

images Ideally same side as the native talus to replace the deficient cartilage with cartilage from the exact same location

images Maximum donor graft available

images Advantage over knee or talar autograft if the OLT proves not to be contained

images Recipient site preparation

images Débride the OLT sharply to stable circumferential rim of articular cartilage (TECH FIG 3A).

images Be sure that the defect is contained.

images Bony rim circumferentially

images Interference fit will be compromised if medial talar dome at the defect lacks integrity.

images If not, then a structural allograft reconstruction should be considered.

images Assess defect size and orientation with the sizing guide and with reference to preoperative CT scan (TECH FIG 3B). Larger defects may warrant two or even three grafts.

images Recipient site chisel

images Assistant will need to position foot in maximal inversion or eversion for medial and lateral OLTs, respectively (TECH FIG 4A).

images Select appropriate chisel size.

images Orient chisel perpendicular to defect(TECH FIG 4B).

images We routinely advance the chisel 11 to 12 mm into the talus (TECH FIG 4C).

images Maintain proper chisel orientation to the desired depth.

images

TECH FIG 3A. The surgeon probes and débrides the osteochondral lesion of the talus to define its superficial dimensions. B. The defect is sized to determine optimal recipient chisel size.

images Do not attempt to change orientation of the chisel once the chisel has been advanced into the subchondral bone.

images Once at the desired depth, twist the chisel forcefully 90 degrees and then 90 degrees again (TECH FIG 4D).

images Gently toggle the chisel to free the diseased cartilage from the surrounding healthy cartilage.

images Extract the diseased osteochondral cylinder (TECH FIG 4E).

images If the subchondral bone is sclerotic, a reamer of corresponding size from an anterior cruciate ligament set may be used to create the recipient site.

images Use cool saline irrigation to limit the risk of heat necrosis to surrounding native talus.

images Predrill the guide pin to ensure that the reamer maintains position and proper orientation.

images Donor site preparation and graft harvest (superior lateral femoral condyle)

images

TECH FIG 4 • Preparing the recipient site. A. Assistant everts the ankle to permit vertical axis of the recipient chisel. B. Recipient chisel is oriented properly on the osteochondral lesion of the talus, approaching without violating the medial talar dome subchondral bone (essential so the defect remains contained). C. Mallet to advance the chisel. D. Once fully seated, the chisel is aggressively twisted to free the diseased cartilage cylinder. E.The recipient site is prepared. Note the slight medial cartilage defect, but the recipient site is still contained.

images Superolateral arthrotomy

images Knee extended

images Longitudinal approach immediately lateral to patella (TECH FIG 5A,B), about 5 cm long

images Avoid injuring cartilage.

images Chose optimal site for graft harvest (TECH FIG 5C).

images Use the same sizing guide as you did for the recipient site to determine the proper trajectory for the harvesting chisel and to determine the ideal location for graft harvest.

images If multiple grafts are needed, be sure to leave an adequate bridge between harvest sites.

images Avoid fracturing one harvest site into another, thereby creating a large defect.

images Select the corresponding donor chisel.

images This chisel is 1 mm larger in diameter than the recipient chisel. This allows for interference fit of the graft into the recipient site.

images The chisel must be perpendicular to the harvest site (TECH FIG 5D).

images Be sure not to contact the cartilage surface with the chisel until proper position has been obtained. The chisel is sharp and will cut into the cartilage, even with light pressure.

images Impact the chisel to a depth of 10 mm (TECH FIG 5E).

images Do not change the orientation of the chisel once it has been advanced into the subchondral bone.

images Once desired depth has been achieved

images Rotate the chisel 90 degrees and then 90 degrees again (TECH FIG 5F).

images Toggle the chisel lightly to release the graft.

images Extract the graft from the knee.

images A fenestration in the chisel allows for visualization of the graft to ensure it is free and advancing from the harvest site with the chisel (TECH FIG 5G,H).

images

images

TECH FIG 5A–C. Exposure of superolateral femoral condyle. A. Superolateral approach to knee. B. Knee arthrotomy. C. Superolateral femoral condyle exposed with patella retracted medially. D–H.Harvesting donor graft. D. Donor chisel oriented to allow optimal graft harvest. E. Harvesting chisel impacted without changing trajectory once chisel introduced. F. Once chisel is fully seated, it is aggressively twisted to free the cylindrical graft. G. Chisel is carefully withdrawn (fenestrations within chisel confirm that the graft is advancing with the chisel). H. Graft extracted and harvest site evident.

images The graft does not leave the chisel until it is secured in the recipient site.

images Graft transfer to the recipient site

images Properly orient the donor chisel over the recipient site, maintaining contact with the chisel directly over the defect (TECH FIG 6A,B).

images Advance the graft into the recipient site by advancing the tamp in the donor chisel (TECH FIG 6C). Fenestrations in the chisel permit visualization of the graft being advanced.

images Remove the chisel when the graft is nearly fully seated (TECH FIG 6D,E).

images The goal is to place the graft flush with the surrounding native articular cartilage.

images A corresponding tamp or sizing guide may then be used to carefully achieve the final position of the graft (TECH FIG 6F,G).

images We routinely harvest a 10-mm osteochondral cylinder but prepare an 11to 12-mm recipient site. While countersinking the graft is a risk, the interference fit typically limits this from occurring. In our opinion it is safer than creating a recipient site that is too shallow, thus potentially leading to forceful tamping of the graft that may lead to shearing of the graft cartilage from its osseous cylinder.

Osteochondral Transfer Incorporating a Small Portion of Medial or Lateral Talar Dome Cartilage

images This technique is used when the OLT involves some of the cartilage on the medial or lateral sides of the talar dome while still being contained.

images Recipient site

images The recipient site chisel approaches the talar shoulder but is not advanced beyond the subchondral border of the medial or lateral talus.

images This will extract the dorsal shoulder of the talus, leaving the medial or lateral talar subchondral bone and cartilage intact (still contained).

images Donor site

images As for the recipient site and chisel, the donor chisel approaches the superolateral femoral condyle's shoulder but is not advanced beyond its border.

images The dorsal shoulder of the graft will be included in the harvest without violating the lateral femoral condyle's subchondral bone on its lateral margin.

images Transfer

images Medial OLT

images The chisel will need to be rotated 180 degrees to fill the articular cartilage defect that extends over the shoulder from the dorsal talar dome.

images

images

TECH FIG 6 • Transfer of graft to recipient site. A. Donor chisel with graft oriented with recipient site. B. Tamp within chisel is advanced to transfer the graft into the recipient site. C. Fenestrations in chisel confirm that graft is advancing. D. Chisel typically releases graft before it is fully seated (in our hands, preferred so we can control the final graft position). E. Graft sitting slightly proud relative to the adjacent native cartilage. F.Dedicated smooth tamp used to perform final seating of graft. Inset shows that the tamp is tapped lightly to advance graft in a graduated manner. G. Graft seated flush with surrounding native cartilage. (Note medial articular defect not fully resurfaced, but majority of osteochondral lesion of the talus is resurfaced with stable graft.)

images Mark the donor chisel during graft harvest to avoid malrotation of the graft in the recipient site.

images For a lateral OLT this rotation is not necessary when transferring from the ipsilateral knee.

Closure

images Medial closure

images Reduction of the medial osteotomy after cartilage reconstruction

images Temporarily place a drill bit in one of the predrilled holes to orient the reduction.

images Confirm reduction by visualizing the anterior and posterior aspects of the osteotomy at the joint line.

images We routinely use two partially threaded small fragment cancellous screws to fix the osteotomy under compression (TECH FIG 7A,B).

images If fixation is suboptimal, two fully threaded cortical screws may be used to engage the opposite cortex. It may be necessary to use longer cortical screws from a pelvic set to reach the opposite cortex.

images

images

TECH FIG 7 • Reducing medial malleolar osteotomy. A. Reduced osteotomy is secured with two malleolar screws placed in the predrilled holes. B. View through arthrotomy confirms reduction of anterior tibial plafond. C.Medial buttress plate. D. Closing posterior tibial tendon sheath and flexor retinaculum. E. Closing anterior capsulotomy. F. Closing lateral knee arthrotomy. G, H. Skin reapproximation. G.Ankle. H. Knee.

images A buttress plate placed at the superior aspect of the osteotomy provides an antiglide effect (TECH FIG 7C).

images Confirm fluoroscopically that the osteotomy is anatomically reduced at the plafond.

images A minimal gap will be present at the osteotomy site despite anatomic reduction, due to the thickness of the saw blade.

images Reapproximate the flexor retinaculum with the PTT in its anatomic position (TECH FIG 7D).

images Close the anterior arthrotomy (TECH FIG 7E).

images The periosteum over the osteotomy may be reapproximated but must be coordinated with the antiglide plate.

images Lateral closure

images Fibular osteotomy reduction, ligament repair, and closure after cartilage procedure

images Fibular osteotomy is reduced, plate is positioned, and screws are placed in predrilled holes. A small gap at the osteotomy site may be visible on fluoroscopic confirmation despite anatomic clinical reduction; this is secondary to saw blade thickness.

images A modified Brostrom ligament repair serves to reattach the anterior talofibular and calcaneofibular ligaments and augment with the inferior extensor retinaculum. We routinely use suture anchors to reattach the ligaments to the fibula. We use a modified Brostrom ligament reattachment after osteochondral transfer for lateral OLTs.

images Close the superolateral capsule of the knee (TECH FIG 7F).

images Close the subcutaneous layer and skin after tourniquet release and meticulous hemostasis for both the knee and ankle (TECH FIG 7G,H).

images We use a drain, unless the wounds have minor residual bleeding.

images

POSTOPERATIVE CARE

images We routinely observe these patients overnight for pain control.

images Follow-up is done in about 10 to 14 days.

images Provided the wound and osteotomy (if one was performed) are stable, the patient is transferred into a touch-down weightbearing cam boot. If not, a touch-down weight-bearing shortleg cast is continued until the wound and osteotomy are stable.

images Intermittent minimal, gentle ankle range of motion (ROM) is encouraged, three or four times a day. If financially feasible, we arrange for an ankle continuous passive motion (CPM) device.

images Touch-down weight bearing is maintained for 8 to 10 weeks, with progressively increasing ankle ROM exercise.

images We routinely obtain simulated weight-bearing radiographs at 6 weeks and 10 weeks, and again at 14 to 16 weeks, depending on the progression of healing. If there was a concern about fixation of the graft or osteotomy, then radiographs are also obtained at the first postoperative visit (FIG 4).

images Knee cartilage has a different thickness than ankle cartilage; therefore, an appropriately placed osteochondral graft from the knee may appear recessed on the postoperative radiograph (FIG 5).

OUTCOMES

images Good to excellent results with osteochondral autografting at short to intermediate follow-up can be obtained in 90% to 94% of patients.

images Excellent functional outcomes

images Improvement in ROM

images Improved pain scores

images Best results for smaller defects (those that can be managed with a single graft)

images Good to excellent results for OLTs associated with subchondral cysts

images Donor site morbidity was found to be minimal except in a single study, which found poor knee functional scores in 36%.

images No reported complications from malleolar osteotomy

images Results are not worse for osteochondral transfer performed as a secondary procedure after failed arthroscopic treatment compared to osteochondral transfer as a primary procedure. Additionally, there may be no benefit of osteochondral autograft transplantation over chondroplasty or microfracture in the management of primary lesions without subchondral cysts, as demonstrated in a recent randomized prospective trial comparing the three procedures.9

COMPLICATIONS

images Infection

images Wound complication

images Failure of graft incorporation

images Graft failure and potential risk of developing degenerative change

images Articular cartilage delamination or fissuring of the graft

images Malleolar osteotomy nonunion

images Persistent pain despite radiographic suggestion of graft incorporation

images Disease transmission with allograft, but with the current screening practices of tissue banks, this risk is negligible

images Donor site morbidity at the knee

images

FIG 4 • Postoperative radiographs. A, B. AP and mortise views showing anatomic reduction of medial malleolar osteotomy. C. Sagittal view.

images

FIG 5 • Different patient undergoing osteochondral transfer. Knee cartilage is thicker than ankle cartilage; thus, despite having anatomic congruency of the graft and adjacent native cartilage, the graft may appear countersunk.

REFERENCES

1. Al-Shaikh RA, Chou LB, Mann JA, et al. Autologous osteochondral grafting for talar cartilage defects. Foot Ankle Int 2002;23:381–389.

2. Baltzer AW, Arnold JP. Bone-cartilage transplantation from the ipsilateral knee for chondral lesions of the talus. Arthroscopy 2005;21: 159–166.

3. Easley ME, Scranton PE, Jr. Osteochondral autologous transfer system. Foot Ankle Clin 2003;8:275–290.

4. Garras DN, Santangelo JA, Wang DW, et al. A quantitative comparison of surgical approaches for posterolateral osteochondral lesions of the talus. Foot Ankle Int 2008;29:415–420.

5. Gobbi A, Francisco RA, Lubowitz JH, et al. Osteochondral lesions of the talus: randomized controlled trial comparing chondroplasty, microfracture, and osteochondral autograft transplantation. [Erratum appears in Arthroscopy 2008 Feb;24(2):A16]. Arthroscopy 2006;22: 1085–1092.

6. Hangody L, Fules P. Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Joint Surg Am 2003; 85A(Suppl 2):25–32.

7. Hangody L, Kish G, Modis L, et al. Mosaicplasty for the treatment of osteochondritis dissecans of the talus: two to seven year results in 36 patients. Foot Ankle Int 2001;22:552–558.

8. Sammarco GJ, Makwana NK. Treatment of talar osteochondral lesions using local osteochondral graft. Foot Ankle Int 2002;23: 693–698.

9. Scranton PE Jr, Frey CC, Feder KS. Outcome of osteochondral autograft transplantation for type-V cystic osteochondral lesions of the talus. J Bone Joint Surg Br 2006;88:614–619.

10. Tochigi Y, Amendola A, Muir D, et al. Surgical approach for centrolateral talar osteochondral lesions with an anterolateral osteotomy. Foot Ankle Int 2002;23:1038–1039.



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