General Principles
Chaper 1. Principles of Antiepileptic Drug Action
Chaper 2. Neurophysiologic Effects of Antiepileptic Drugs
Chaper 3. Discovery and Preclinical Development of Antiepileptic Drugs
Chaper 4. New Antiepileptic Drug Development: Medical Perspective
Chaper 5. Clinical Development of Antiepileptic Drugs: Industry Perspective
Chaper 6. The Development of Antiepileptic Drugs: Regulatory Perspective
Chaper 7. Antiepileptic Drug Monotherapy in Adults: Selection and Use in New-Onset Epilepsy
Chaper 8. Combination Therapy and Drug Interactions
Chaper 9. Laboratory Monitoring of Antiepileptic Drugs
Chaper 10. Safety Monitoring of Antiepileptic Drugs
Chaper 11. Use of Antiepileptic Drugs in Children
Chaper 12. Antiepileptic Drug Use in Women
Chaper 13. Epilepsy in the Elderly
Chaper 14. Treatment of Status Epilepticus
Chaper 15. Prevention of Epileptogenesis
Benzodiazepines
Chaper 16. Mechanisms of Action
Chaper 17. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 18. Clinical Efficacy and Use in Epilepsy
Carbamazepine
Chaper 20. Mechanisms of Action
Chaper 21. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 22. Interactions with Other Drugs
Chaper 23. Clinical Efficacy and USE in Epilepsy
Chaper 24. Clinical Efficacy and USE in Other Neurologic Disorders
Chaper 25. Clinical Efficacy and USE in Psychiatric Disorders
Felbamate
<Gabapentin
Chaper 28. Mechanisms of Action
Chaper 29. Chemistry, Biotransformation, Pharmacokinetics, and Interactions
Chaper 31. Clinical Efficacy and Use in Other Neurological Disorders
Chaper 32. Clinical Efficacy and Use in Psychiatric Disorders
Lamotrigine
Chaper 34. Mechanisms of Action
Chaper 35. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 36. Interaction with Other Drugs
Chaper 37. Clinical Efficacy and Use in Epilepsy
Chaper 38. Efficacy and Use in Psychiatric Disorders
Levetiracetam
Chaper 40. Mechanisms of Action
Chaper 41. Chemistry, Biotransformation, Pharmacokinetics, and Drug Interactions
Chaper 43. Adverse Experiences
Oxcarbazepine
Chaper 44. Mechanisms of Action
Chaper 45. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 46. Interactions with Other Drugs
Chaper 47. Clinical Efficacy and Use in Epilepsy
Chaper 48. Clinical Efficacy and Use in Psychiatric Disorders
Phenobarbital and Other Barbiturates
Chaper 50. Mechanisms of Action
Chaper 51. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 52. Interactions With Other Drugs
Chaper 53. Clinical Efficacy and Use in Epilepsy
Chaper 54. Clinical Efficacy and Use in Nonepileptic Disorders
Chaper 56. Methylphenobarbital
Phenytoin and Other Hydantoins
Chaper 57. Mechanisms of Action
Chaper 58. Chemistry and Biotransformation
Chaper 59. Interactions with Other Drugs
Chaper 60. Clinical Efficacy and Use in Epilepsy
Chaper 61. Clinical Efficacy and Use in Other Neurological Disorders
Chaper 62. Clinical Efficacy and Use in Psychiatric Disorders
Primidone
Succinimides
Chaper 66. Mechanisms of Action
Chaper 67. Ethosuximide: Chemistry, Biotransformation, Pharmacokinetics, and Drug Interactions
Chaper 68. Clinical Efficacy and Use in Epilepsy
Tiagabine
Chaper 71. Mechanisms of Action
Chaper 72. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 74. Clinical Efficacy and Use in Epilepsy
Chaper 75. Clinical Efficacy and Use in Nonepileptic Disorders
Topiramate
Chaper 77. Mechanisms of Action
Chaper 78. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 80. Clinical Efficacy and Use in Epilepsy
Chaper 81. Clinical Efficacy and Use in Nonepileptic Disorders
Valproic Acid
Chaper 83. Mechanisms of Action
Chaper 84. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 86. Clinical Efficacy and Use in Epilepsy
Chaper 87. Clinical Efficacy and Use in Other Neurological Disorders
Chaper 88. Clinical Efficacy and Use in Psychiatric Disorders
Vigabatrin
Zonisamide
Chaper 91. Mechanisms of Action
Chaper 92. Chemistry, Biotransformation, and Pharmacokinetics
Chaper 94. Clinical Efficacy and Use in Epilepsy
Drugs in Development
Chaper 98. Drugs in Early Clinical Development