Basic & Clinical Biostatistics, 4th Edition

Appendices

CHAPTER GUIDE TO STATISTICAL TESTS IN BASIC & CLINICAL BIOSTATISTICS

Figure. No caption available.

Appendix A: Tables

Table A-1. Random numbers.

927415

956121

168117

169280

326569

266541

926937

515107

014658

159944

821115

317592

867169

388342

832261

993050

639410

698969

867169

542747

032683

131188

926198

371071

512500

843384

085361

398488

774767

383837

062454

423050

670884

840940

845839

979662

806702

881309

772977

367506

729850

457758

837815

163631

622143

938278

231305

219737

926839

453853

767825

284716

916182

467113

854813

731620

978100

589512

147694

389180

851595

452454

262448

688990

461777

647487

449353

556695

806050

123754

722070

935916

169116

586865

756231

469281

258737

989450

139470

358095

528858

660128

342072

681203

433775

761861

107191

515960

759056

150336

221922

232624

398839

495004

881970

792001

740207

078048

854928

875559

246288

000144

525873

755998

866034

444933

785944

018016

734185

499711

254256

616625

243045

251938

773112

463857

781983

078184

380752

492215

638951

982155

747821

773030

594005

526828

868888

769341

477611

628714

250645

853454

611034

167642

701316

589251

330456

681722

379290

955292

664549

656401

320855

215201

411257

411484

068629

050150

106933

900095

407167

435509

578642

268724

366564

511815

895893

438644

330273

590506

820439

976891

986683

830515

284065

813310

554920

111395

335421

814351

508062

663801

365001

924418

927660

793888

507773

975109

625175

552278

957559

236000

471608

888683

146821

034687

694904

499959

950969

085327

352611

335924

863016

494926

871064

665892

076333

990558

876958

865769

882966

236535

541645

819783

619813

221175

370697

566925

705564

472934

476626

646911

337167

865652

195448

116729

578292

863854

145858

206557

430943

591126

286553

981699

232269

819656

867825

890737

819064

712344

033613

457019

478176

342104

383035

043025

201591

127424

771948

762990

879392

378486

198814

928028

493486

373709

924020

273258

851781

003514

685749

713570

502523

157212

472643

439301

718562

196269

815316

651530

080430

912635

820240

533626

914984

444954

053723

079387

530020

703312

312248

619263

715357

923412

252522

913950

030964

407872

419563

426527

565215

243717

870561

984049

445361

315827

651925

464440

820157

006091

670091

478357

490641

082559

519649

761345

761354

794613

330132

319843

Table A-2. Areas under the standard normal curve.a

z

Area Between -z & +z

Area in Two Tails (< -z & > +z)

Area in One Tail
(< -z or > +z)

0.00

0.000

1.000

0.500

0.05

0.040

0.960

0.480

0.10

0.080

0.920

0.460

0.15

0.119

0.881

0.440

0.20

0.159

0.841

0.421

0.25

0.197

0.803

0.401

0.30

0.236

0.764

0.382

0.35

0.274

0.726

0.363

0.40

0.311

0.689

0.345

0.45

0.347

0.653

0.326

0.50

0.383

0.617

0.309

0.55

0.418

0.582

0.291

0.60

0.451

0.549

0.274

0.65

0.484

0.516

0.258

0.70

0.516

0.484

0.242

0.75

0.547

0.453

0.227

0.80

0.576

0.424

0.212

0.85

0.605

0.395

0.198

0.90

0.632

0.368

0.184

0.95

0.658

0.342

0.171

1.00a

0.683

0.317

0.159

1.05

0.706

0.294

0.147

1.10

0.729

0.271

0.136

1.15

0.750

0.250

0.125

1.20

0.770

0.230

0.115

1.25

0.789

0.211

0.106

1.28a

0.800

0.200

0.100

1.30

0.806

0.194

0.097

1.35

0.823

0.177

0.089

1.40

0.838

0.162

0.081

1.45

0.853

0.147

0.074

1.50

0.866

0.134

0.067

1.55

0.879

0.121

0.061

1.60

0.890

0.110

0.055

1.645a

0.900

0.100

0.050

1.65

0.901

0.099

0.049

1.70

0.911

0.089

0.045

1.75

0.920

0.080

0.040

1.80

0.928

0.072

0.036

1.85

0.936

0.064

0.032

1.90

0.943

0.057

0.029

1.95

0.949

0.051

0.026

1.96a

0.950

0.050

0.025

2.00

0.954

0.046

0.023

2.05

0.960

0.040

0.020

2.10

0.964

0.036

0.018

2.15

0.968

0.032

0.016

2.20

0.972

0.028

0.014

2.25

0.976

0.024

0.012

2.30

0.979

0.021

0.011

2.326a

0.980

0.020

0.010

2.35

0.981

0.019

0.009

2.40

0.984

0.016

0.008

2.45

0.986

0.014

0.007

2.50

0.988

0.012

0.006

2.55

0.989

0.011

0.005

2.575a

0.990

0.010

0.005

2.60

0.991

0.009

0.005

2.65

0.992

0.008

0.004

2.70

0.993

0.007

0.003

2.75

0.994

0.006

0.003

2.80

0.995

0.005

0.003

2.85

0.996

0.004

0.002

2.90

0.996

0.004

0.002

2.95

0.997

0.003

0.002

3.00

0.997

0.003

0.001

aCommonly used values are underlined.
Source: Adapted and reproduced, with permission, from Table 1 in Pearson ES, Hartley HO (editors):Biometrika Tables for Statisticians, 3rd ed, Vol 1. Cambridge University Press, 1966. Used with the kind permission of the Biometrika trustees.

Table A-3. Percentage points or critical values for the t distribution corresponding to commonly used areas under the curve.

Degrees of Freedom

Area in 1 Tail

0.05

0.025

0.01

0.005

0.0005

Area in 2 Tails

0.10

0.05

0.02

0.01

0.001

1

6.314

12.706

31.821

63.657

636.62

2

2.920

4.303

6.965

9.925

31.598

3

2.353

3.182

4.541

5.841

12.924

4

2.132

2.776

3.747

4.604

8.610

5

2.015

2.571

3.365

4.032

6.869

6

1.943

2.447

3.143

3.707

5.959

7

1.895

2.365

2.998

3.499

5.408

8

1.860

2.306

2.896

3.355

5.041

9

1.833

2.262

2.821

3.250

4.781

10

1.812

2.228

2.764

3.169

4.587

11

1.796

2.201

2.718

3.106

4.437

12

1.782

2.179

2.681

3.055

4.318

13

1.771

2.160

2.650

3.012

4.221

14

1.761

2.145

2.624

2.977

4.140

15

1.753

2.131

2.602

2.947

4.073

16

1.746

2.120

2.583

2.921

4.015

17

1.740

2.110

2.567

2.898

3.965

18

1.734

2.101

2.552

2.878

3.922

19

1.729

2.093

2.539

2.861

3.883

20

1.725

2.086

2.528

2.845

3.850

21

1.721

2.080

2.518

2.831

3.819

22

1.717

2.074

2.508

2.819

3.792

23

1.714

2.069

2.500

2.807

3.767

24

1.711

2.064

2.492

2.797

3.745

25

1.708

2.060

2.485

2.787

3.725

26

1.706

2.056

2.479

2.779

3.707

27

1.703

2.052

2.473

2.771

3.690

28

1.701

2.048

2.467

2.763

3.674

29

1.699

2.045

2.462

2.756

3.659

30

1.697

2.042

2.457

2.750

3.646

40

1.684

2.021

2.423

2.704

3.551

60

1.671

2.000

2.390

2.660

3.460

120

1.658

1.980

2.358

2.617

3.373

1.645

1.960

2.326

2.576

3.291

Source: Adapted and reproduced, with permission, from Table 12 in Pearson ES, Hartley HO (editors):Biometrika Tables for Statisticians, 3rd ed, Vol 1. Cambridge University Press, 1966. Used with the kind permission of the Biometrika Trustees.

Table A-4. Percentage points or critical values for the F distribution corresponding to areas of 0.05 and 0.01 under the upper tail of the distribution.

Degrees of Freedom, Denominator

Area

Degrees of Freedom, Numerator

1

2

3

4

5

6

7

8

9

10

12

15

20

24

30

40

60

120

1

0.05

161.4

199.5

215.7

224.6

230.2

234.2

236.8

238.9

240.5

241.9

243.9

245.9

248.0

249.1

250.1

251.1

252.2

253.3

254.3

0.01

4052

4999.5

5403

5625

5764

5859

5928

5981

6022

6056

6106

6157

6209

6235

6261

6287

6313

6339

6366

2

0.05

18.51

19.00

19.16

19.25

19.30

19.33

19.35

19.37

19.38

19.40

19.41

19.43

19.45

19.45

19.46

19.47

19.48

19.49

19.50

0.01

98.50

99.00

99.17

99.25

99.30

99.33

99.36

99.37

99.39

99.40

99.42

99.43

99.45

99.46

99.47

99.47

99.48

99.49

99.50

3

0.05

10.13

9.55

9.28

9.12

9.01

8.94

8.89

8.85

8.81

8.79

8.74

8.70

8.66

8.64

8.62

8.59

8.57

8.55

8.53

0.01

34.12

30.82

29.46

28.71

28.24

27.91

27.67

27.49

27.35

27.23

27.05

26.87

26.69

26.60

26.50

26.41

26.32

26.22

26.13

4

0.05

7.71

6.94

6.59

6.39

6.26

6.16

6.09

6.04

6.00

5.96

5.91

5.86

5.80

5.77

5.75

5.72

5.69

5.66

5.63

0.01

21.20

18.00

16.69

15.98

15.52

15.21

14.98

14.80

14.66

14.55

14.37

14.20

14.02

13.93

13.84

13.75

13.65

13.56

13.46

5

0.05

6.61

5.79

5.41

5.19

5.05

4.95

4.88

4.82

4.77

4.74

4.68

4.62

4.56

4.53

4.50

4.46

4.43

4.40

4.36

0.01

16.26

13.27

12.06

11.39

10.97

10.67

10.46

10.29

10.16

10.05

9.89

9.72

9.55

9.47

9.38

9.29

9.20

9.11

9.02

6

0.05

5.99

5.14

4.76

4.53

4.39

4.28

4.21

4.15

4.10

4.06

4.00

3.94

3.87

3.84

3.81

3.77

3.74

3.70

3.67

0.01

13.75

10.92

9.78

9.15

8.75

8.47

8.26

8.10

7.98

7.87

7.72

7.56

7.40

7.31

7.23

7.14

7.06

6.97

6.88

7

0.05

5.59

4.74

4.35

4.12

3.97

3.87

3.79

3.73

3.68

3.64

3.57

3.51

3.44

3.41

3.38

3.34

3.30

3.27

3.23

0.01

12.25

9.55

8.45

7.85

7.46

7.19

6.99

6.84

6.72

6.62

6.47

6.31

6.16

6.07

5.99

5.91

5.82

5.74

5.65

8

0.05

5.32

4.46

4.07

3.84

3.69

3.58

3.50

3.44

3.39

3.35

3.28

3.22

3.15

3.12

3.08

3.04

3.01

2.97

2.93

0.01

11.26

8.65

7.59

7.01

6.63

6.37

6.18

6.03

5.91

5.81

5.67

5.52

5.36

5.28

5.20

5.12

5.03

4.95

4.86

9

0.05

5.12

4.26

3.86

3.63

3.48

3.37

3.29

3.23

3.18

3.14

3.07

3.01

2.94

2.90

2.86

2.83

2.79

2.75

2.71

0.01

10.56

8.02

6.99

6.42

6.06

5.80

5.61

5.47

5.35

5.26

5.11

4.96

4.81

4.73

4.65

4.57

4.48

4.40

4.31

10

0.05

4.96

4.10

3.71

3.48

3.33

3.22

3.14

3.07

3.02

2.98

2.91

2.85

2.77

2.74

2.70

2.66

2.62

2.58

2.54

0.01

10.04

7.56

6.55

5.99

5.64

5.39

5.20

5.06

4.94

4.85

4.71

4.56

4.41

4.33

4.25

4.17

4.08

4.00

3.91

12

0.05

4.75

3.89

3.49

3.26

3.11

3.00

2.91

2.85

2.80

2.75

2.69

2.62

2.54

2.51

2.47

2.43

2.38

2.34

2.30

0.01

9.33

6.93

5.95

5.41

5.06

4.82

4.64

4.50

4.39

4.30

4.16

4.01

3.86

3.78

3.70

3.62

3.54

3.45

3.36

15

0.05

4.54

3.68

3.29

3.06

2.90

2.79

2.71

2.64

2.59

2.54

2.48

2.40

2.33

2.29

2.25

2.20

2.16

2.11

2.07

0.01

8.68

6.36

5.42

4.89

4.56

4.32

4.14

4.00

3.89

3.80

3.67

3.52

3.37

3.29

3.21

3.13

3.05

2.96

2.87

20

0.05

4.35

3.49

3.10

2.87

2.71

2.60

2.51

2.45

2.39

2.35

2.28

2.20

2.12

2.08

2.04

1.99

1.95

1.90

1.84

0.01

8.10

5.85

4.94

4.43

4.10

3.87

3.70

3.56

3.46

3.37

3.23

3.09

2.94

2.86

2.78

2.69

2.61

2.52

2.42

24

0.05

4.26

3.40

3.01

2.78

2.62

2.51

2.42

2.36

2.30

2.25

2.18

2.11

2.03

1.98

1.94

1.89

1.84

1.79

1.73

0.01

7.82

5.61

4.72

4.22

3.90

3.67

3.50

3.36

3.26

3.17

3.03

2.89

2.74

2.66

2.58

2.49

2.40

2.31

2.21

30

0.05

4.17

3.32

2.92

2.69

2.53

2.42

2.33

2.27

2.21

2.16

2.09

2.01

1.93

1.89

1.84

1.79

1.74

1.68

1.62

0.01

7.56

5.39

4.51

4.02

3.70

3.47

3.30

3.17

3.07

2.98

2.84

2.70

2.55

2.47

2.39

2.30

2.21

2.11

2.01

40

0.05

4.08

3.23

2.84

2.61

2.45

2.34

2.25

2.18

2.12

2.08

2.00

1.92

1.84

1.79

1.74

1.69

1.64

1.58

1.51

0.01

7.31

5.18

4.31

3.83

3.51

3.29

3.12

2.99

2.89

2.80

2.66

2.52

2.37

2.29

2.20

2.11

2.02

1.92

1.80

60

0.05

4.00

3.15

2.76

2.53

2.37

2.25

2.17

2.10

2.04

1.99

1.92

1.84

1.75

1.70

1.65

1.59

1.53

1.47

1.39

0.01

7.08

4.98

4.13

3.65

3.34

3.12

2.95

2.82

2.72

2.63

2.50

2.35

2.20

2.12

2.03

1.94

1.84

1.73

1.60

120

0.05

3.92

3.07

2.68

2.45

2.29

2.17

2.09

2.02

1.96

1.91

1.83

1.75

1.66

1.61

1.55

1.50

1.43

1.35

1.25

0.01

6.85

4.79

3.95

3.48

3.17

2.96

2.79

2.66

2.56

2.47

2.34

2.19

2.03

1.95

1.86

1.76

1.66

1.53

1.38

0.05

3.84

3.00

2.60

2.37

2.21

2.10

2.01

1.94

1.88

1.83

1.75

1.67

1.57

1.52

1.46

1.39

1.32

1.22

1.00

0.01

6.63

4.61

3.78

3.32

3.02

2.80

2.64

2.51

2.41

2.32

2.18

2.04

1.88

1.79

1.70

1.59

1.47

1.32

1.00

Source: Adapted and reproduced, with permission, from Table 18 in Pearson ES, Hartley HO (editors): Biometrika Tables for Statisticians, 3rd ed, Vol 1. Cambridge University Press, 1966. Used with the kind permission of the Biometrika Trustees.

Table A-5. Percentage points or critical values for the χ2 distribution corresponding to commonly used areas under the curve.

Degrees of Freedom

Area in Upper Tail

0.10

0.05

0.01

0.001

1

2.706

3.841

6.635

10.828

2

4.605

5.991

9.210

13.816

3

6.251

7.815

11.345

16.266

4

7.779

9.488

13.277

18.467

5

9.236

11.071

15.086

20.515

6

10.645

12.592

16.812

22.458

7

12.017

14.067

18.475

24.322

8

13.362

15.507

20.090

26.125

9

14.684

16.919

21.666

27.877

10

15.987

18.307

23.209

29.588

11

17.275

19.675

24.725

31.264

12

18.549

21.026

26.217

32.909

13

19.812

22.362

27.688

34.528

14

21.064

23.685

29.141

36.123

15

22.307

24.996

30.578

37.697

16

23.542

26.296

32.000

39.252

17

24.769

27.587

33.409

40.790

18

25.989

28.869

34.805

42.312

19

27.204

30.144

36.191

43.820

20

28.412

31.410

37.566

45.315

21

29.615

32.671

38.932

46.797

22

30.813

33.924

40.289

48.268

23

32.007

35.173

41.638

49.728

24

33.196

36.415

42.980

51.179

25

34.382

37.653

44.314

52.620

26

35.563

38.885

45.642

54.052

27

36.741

40.113

46.963

55.476

28

37.916

41.337

48.278

56.892

29

39.088

42.557

49.588

58.302

30

40.256

43.773

50.892

59.703

40

51.805

55.759

63.691

73.402

50

63.167

67.505

76.154

86.661

60

74.397

79.082

88.379

99.607

70

85.527

90.531

100.425

112.317

80

96.578

101.879

112.329

124.839

90

107.565

113.145

124.116

137.208

100

118.498

124.342

135.807

149.449

Source: Adapted and reproduced, with permission, from Table 8 in Pearson ES, Hartley HO (editors):Biometrika Tables for Statisticians, 3rd ed, Vol 1. Cambridge University Press, 1966. Used with the kind permission of the Biometrika Trustees.

Table A-6. z Transformationa of the correlation coefficient.

r

z

r

z

0.00

0.000

0.50

0.549

0.01

0.010

0.51

0.563

0.02

0.020

0.52

0.576

0.03

0.030

0.53

0.590

0.04

0.040

0.54

0.604

0.05

0.050

0.55

0.618

0.06

0.060

0.56

0.633

0.07

0.070

0.57

0.648

0.08

0.080

0.58

0.663

0.09

0.090

0.59

0.678

0.10

0.100

0.60

0.693

0.11

0.110

0.61

0.709

0.12

0.121

0.62

0.725

0.13

0.131

0.63

0.741

0.14

0.141

0.64

0.758

0.15

0.151

0.65

0.775

0.16

0.161

0.66

0.793

0.17

0.172

0.67

0.811

0.18

0.182

0.68

0.829

0.19

0.192

0.69

0.848

0.20

0.203

0.70

0.867

0.21

0.213

0.71

0.887

0.22

0.224

0.72

0.908

0.23

0.234

0.73

0.929

0.24

0.245

0.74

0.951

0.25

0.255

0.75

0.973

0.26

0.266

0.76

0.996

0.27

0.277

0.77

1.020

0.28

0.288

0.78

1.045

0.29

0.299

0.79

1.071

0.30

0.310

0.80

1.099

0.31

0.321

0.81

1.127

0.32

0.332

0.82

1.157

0.33

0.343

0.83

1.188

0.34

0.354

0.84

1.221

0.35

0.365

0.85

1.256

0.36

0.377

0.86

1.293

0.37

0.388

0.87

1.333

0.38

0.400

0.88

1.376

0.39

0.412

0.89

1.422

0.40

0.424

0.90

1.472

0.41

0.436

0.91

1.528

0.42

0.448

0.92

1.589

0.43

0.460

0.93

1.658

0.44

0.472

0.94

1.738

0.45

0.485

0.95

1.832

0.46

0.497

0.96

1.946

0.47

0.510

0.97

2.092

0.48

0.523

0.98

2.298

0.49

0.536

0.99

2.647

az = 1/2 {ln[(1 + r)/(1 - r)]}.
Source: Adapted and reproduced, with permission, from Table 14 in Pearson ES, Hartley HO (editors):Biometrika Tables for Statisticians, 3rd ed, Vol 1. Cambridge University Press, 1966. Used with the kind permission of the Biometrika Trustees.

Figure A-1. 95% Confidence intervals for population proportion. (Adapted and reproduced, with permission, from Pearson ES, Hartley HO (editors): Biometrika Tables for Statisticians, 3rd ed., Vol. 1. Cambridge University Press, 1966.)



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