Diuretic
PREGNANCY RECOMMENDATION: Compatible
BREASTFEEDING RECOMMENDATION: Compatible
PREGNANCY SUMMARY
Chlorthalidone is structurally related to the thiazide diuretics (see Chlorothiazide). In general, diuretics are not recommended for the treatment of gestational hypertension because of the maternal hypovolemia characteristic of this disease.
FETAL RISK SUMMARY
Reproduction studies in rats and rabbits at doses up to 420 times the human dose have observed no evidence of fetal harm (1).
BREASTFEEDING SUMMARY
See CHLOROTHIAZIDE
Reference
1.Product information. Thalitone. Monarch Pharmaceuticals, 2000.