Antilipemic
PREGNANCY RECOMMENDATION: No Human Data—Probably Compatible
BREASTFEEDING RECOMMENDATION: No Human Data—Probably Compatible
PREGNANCY SUMMARY
Although formerly used to treat hypothyroidism, the drug is now used exclusively for the therapy of hyperlipidemia. Except for the one report below, no mention of its use in human pregnancy has been located.
FETAL RISK SUMMARY
Dextrothyroxine is the dextro-isomer of levothyroxine (see also Levothyroxine). In a study of placental passage of dextrothyroxine, approximately 9% of a radiolabeled dose given 2–8 hours before delivery was found in the cord blood (1).
BREASTFEEDING SUMMARY
No reports describing the use of dextrothyroxine during human lactation have been located.
Reference
1.Kearns JE, Hutson W. Tagged isomers and analogues of thyroxine (their transmission across the human placenta and other studies). J Nucl Med 1963;4:453–61.