Serum
PREGNANCY RECOMMENDATION: Compatible
BREASTFEEDING RECOMMENDATION: No Human Data—Probably Compatible
PREGNANCY SUMMARY
Rabies immune globulin is used to provide passive immunity following exposure to rabies combined with active immunization with rabies vaccine (1). Because rabies is nearly 100% fatal if contracted, both the immune globulin and the vaccine should be given for postexposure prophylaxis (1). No risk to the fetus from the immune globulin has been reported (see also Vaccine, Rabies [Human]) (1–3). The American College of Obstetricians and Gynecologists recommends use of rabies immune globulin in pregnancy for postexposure prophylaxis (1).
BREASTFEEDING SUMMARY
No reports describing the use of rabies immune globulin during human lactation have been located.
References
1.American College of Obstetricians and Gynecologists. Immunization during pregnancy. Technical Bulletin. No. 160, October 1991.
2.Amstey MS. Vaccination in pregnancy. Clin Obstet Gynaecol 1983;10:13–22.
3.CDC. Guidelines for vaccinating pregnant women. Available at www.cdc.gov/vaccines/pubs/preg-guide.htm. Accessed May 16, 2010.