Antiarrhythmic
PREGNANCY RECOMMENDATION: No Human Data—Animal Data Suggest Low Risk
BREASTFEEDING RECOMMENDATION: Limited Human Data—Probably Compatible
PREGNANCY SUMMARY
No reports of the use of moricizine in human pregnancy have been located. It is an orally active agent used in the treatment of ventricular tachycardia. The drug is neither teratogenic nor fetotoxic in rats and rabbits at doses up to 6.7 and 4.7 times the maximum recommended human dose, respectively (1).
BREASTFEEDING SUMMARY
The excretion of moricizine in human milk has been documented in one patient (data on file, Roberts Pharmaceutical Corporation, 1993), but no details on the amount in milk or its relationship to maternal levels are available. The clinical significance to the nursing infant is unknown.
Reference
1.Product information. Ethmozine. Roberts Pharmaceutical, 2000.