Pediculicide
PREGNANCY RECOMMENDATION: No Human Data—Probably Compatible
BREASTFEEDING RECOMMENDATION: No Human Data—Probably Compatible
PREGNANCY SUMMARY
Pyrethrins with piperonyl butoxide is a synergistic combination product used topically for the treatment of lice infestations. It is considered the drug of choice for lice (1). Although no reports of its use in pregnancy have been located, topical absorption is poor, so potential toxicity should be less than that of lindane (see also Lindane) (2). For this reason, use of the combination is probably preferred over lindane in the pregnant patient.
BREASTFEEDING SUMMARY
No reports describing the use of pyrethrins with piperonyl butoxide during human lactation have been located. Because the drug is absorbed poorly after topical application, exposure of a nursing infant from breast milk is probably nil.
References
1.Anonymous. Drugs for parasitic infections. In Handbook for Antimicrobial Therapy. New Rochelle, NY: The Medical Letter, Inc., 1984:100.
2.Robinson DH, Shepherd DA. Control of head lice in schoolchildren. Curr Ther Res 1980;27:1–6.