Part I – Science of Clinical Oncology
Section A – Biology and Cancer
Chapter 1 – Molecular Tools in Cancer Research
Chapter 2 – Intracellular Signaling
Chapter 3 – The Cellular Microenvironment and Metastases
Chapter 4 – Control of the Cell Cycle
Chapter 5 – Cell Life and Death
Chapter 7 – Stem Cells, Cell Differentiation, and Cancer
Chapter 8 – Vascular and Interstitial Biology of Tumors
Section B – Genesis of Cancer
Chapter 9 – Environmental Factors
Chapter 10 – DNA Damage Response Pathways and Cancer
Chapter 11 – Viruses and Human Cancer
Chapter 12 – Genetic Factors: Hereditary Cancer Predisposition Syndromes
Chapter 13 – Genetic Factors: Finding Cancer Susceptibility Genes
Chapter 14 – Progressing from Gene Mutations to Cancer
Chapter 15 – Immunodeficiency and Cancer
Section C – Diagnosing Cancer: Pathology and Laboratory Medicine
Chapter 16 – Principles of Oncologic Surgical Pathology
Chapter 17 – Flow Cytometry in Oncologic Diagnosis
Chapter 18 – Conventional and Molecular Cytogenetics of Neoplasia
Chapter 19 – Molecular Diagnostics
Chapter 20 – Biomarkers for Cancer Diagnostics
Section D – Preventing and Treating Cancer
Chapter 22 – Biostatistics and Bioinformatics in Clinical Trials
Chapter 23 – Structures Supporting Cancer Clinical Trials
Chapter 24 – Economic Analysis of Cancer Treatment
Chapter 25 – Use of Epidemiology in Oncology
Chapter 26 – Cancer Prevention, Screening, and Early Detection
Chapter 27 – Nicotine Dependence: Current Treatments and Future Directions
Chapter 28 – Surgical Interventions in Cancer
Chapter 29 – Basics of Radiation Therapy
Chapter 31 – Principles of Molecularly Targeted Therapy: Present and Future
Chapter 32 – Hematopoietic Stem Cell Transplantation
Chapter 33 – Gene Therapy in Oncology
Chapter 34 – Therapeutic Antibodies and Immunologic Conjugates
Chapter 35 – Complementary and Alternative Medicine
Part II – Problems Common to Cancer and its Therapy
Section A – Symptom Management and Palliative Care
Chapter 37 – Rehabilitation of Individuals with Cancer
Chapter 39 – Nausea and Vomiting
Chapter 40 – Oral Complications
Chapter 41 – Alopecia and Cutaneous Complications
Chapter 44 – Caring for Patients at the End of Life
Section B – Hematologic Problems
Chapter 45 – Disorders of Blood Cell Production in Clinical Oncology
Chapter 46 – Diagnosis, Treatment, and Prevention of Cancer-Related Venous Thrombosis
Section C – Infections
Chapter 47 – Infection in the Patient with Cancer
Section D – Metabolic and Paraneoplastic Syndromes
Chapter 50 – Tumor Lysis Syndrome
Chapter 51 – Paraneoplastic Neurologic Syndromes
Section E – Surgical Problems
Chapter 52 – Establishing and Maintaining Vascular Access
Chapter 53 – Acute Abdomen, Bowel Obstruction, and Fistula
Section F – Local Effects of Cancer and Its Metastasis
Chapter 54 – Superior Vena Cava Syndrome
Chapter 55 – Spinal Cord Compression
Chapter 56 – Brain Metastases and Neoplastic Meningitis
Section G – Complications of Therapy
Chapter 61 – Neurologic Complications
Chapter 62 – Pulmonary Complications of Anticancer Treatment
Chapter 63 – Cardiac Effects of Cancer Therapy
Chapter 64 – Reproductive Complications
Chapter 65 – Endocrine Complications
Chapter 66 – Second Malignant Neoplasms
Section H – Special Populations
Chapter 67 – Cancer in the Elderly: Biology, Prevention, and Treatment
Chapter 68 – Special Issues in Pregnancy
Chapter 69 – HIV-Associated Malignancies
Part III – Specific Malignancies
Chapter 70 – Cancer of the Central Nervous System
Chapter 71 – Eye, Orbit, and Adnexal Structures
Chapter 72 – Cancer of the Head and Neck
Chapter 74 – Nonmelanoma Skin Cancers: Basal Cell and Squamous Cell Carcinomas
Chapter 75 – Cancer of the Endocrine System
Chapter 76 – Cancer of the Lung: Non-Small Cell Lung Cancer and Small Cell Lung Cancer