Pocket Emergency Medicine (Pocket Notebook Series) 3rd Ed.

CHF/ACUTE PULMONARY EDEMA

Definition

• CHF: State where heart’s ability to pump is insufficient to meet metabolic needs; can be L-sided or R-sided & systolic or diastolic (ie, failure w/ nl EF)

• Acute pulmonary edema: Fluid in pulmonary interstitium & alveoli 2° L-sided failure/↑ pressure

Approach

• Determine & tx underlying cause

• Intubate immediately for respiratory failure, but consider CPAP/BiPAP if possible

History

• SOB, DOE, CP, cough, orthopnea, PND; if severe, may have severe respiratory distress w/ pink/white sputum, altered mental status (AMS)

Findings

• ↑ BP, ↑ HR, ↑ RR, cardiac dysrhythmia

• +S3 (systolic failure) +S4 (diastolic failure)

• L-sided: +rales; R-sided: Leg edema, JVD, ↑ liver size, +hepatojugular reflex

Evaluation

• Primary Dx is clinical

• POC thoracic/cardiac ultrasound: B-lines (“lung rockets”), decreased EF

• ECG: LVH, tachyarrhythmia, L-heart strain, ischemia, e/o old infarction(s)

CXR (perform @ bedside if unstable): Pulmonary edema, pl effusion, ↑ heart size

• Labs: CBC, lytes, Cr, cardiac markers, BNP or NT-proBNP

• BNP: If dyspnea & BNP >100 → CHF (sens 90%, spec 76%, NEJM 2002;347:161)

• False +: Large PE, cor pulmonale, ESRD; in chronic CHF must compare to “dry weight BNP”

• NT-proBNP: If dyspnea & NT-proBNP >300 → CHF (sens 99%, spec 60%); ↑ cutoff w/ ↑ age; same false+ as BNP

Treatment “LMNOP”

L: Lasix (2× pts home oral dose given IV, or 80 IV)

• Furosemide PO to IV conversion 2:1 (ie, 40 mg PO equiv to 20 mg IV)

• Furosemide 40 mg = torsemide 10 mg = bumetanide 1 mg

• No difference in IV to PO conversions for torsemide or bumetanide

• If allergy to furosemide/torsemide/bumetanide, can use ethacrynic acid

M: Morphine: Venodilator, ↓ dyspnea, ↓ afterload – caution w/ dosing in elderly

*Caution: May be a/w greater frequency of mechanical ventilation, prolonged hospitalization, ICU admission & mortality (Emerg Med J 2008;25(4)205)

N: Nitrates (0.4 mg SL or 10–100 mcg/min IV): Caution in pts w/ AS → ↓ BP 2° preload dep; Nitroprusside if NTG ineffective; nesiritide may ↑ Cr/mortality compared to noninotropic tx (JAMA2005;293:1900)

O: O2: 100% NRB

P: PPV: CPAP or BiPAP for ↓ SaO2 or NRB; ↓ mort/need for intubation (JAMA 2005;294:3124; Lancet 2006;367:1155), ? ↑ effect CPAP c/w BiPAP. Intubate for unconsciousness, severe respiratory distress or visibly tiring after LMNOP tx.

Inotropes: Only for cardiogenic shock. Routine use is a/w increased mortality. Dopamine, dobutamine, milrinone.

• Other: Sit pt up, Foley (assess ins/outs), IABP/LVAD (for severe cardiogenic shock)

Disposition

• D/C: If mild exacerbation of chronic CHF, benign etiology (ie, dietary indiscretion), & pt has close f/u

• EDOU: Selected HF pts can be managed by a rapid tx protocol in the OU w/ fewer bed days & similar readmission rates to admitted pts (Acad Emerg Med 2013;20(6)554)

• Tele: Most pts require admission/Δs to tx regimen before d/c home

• ICU: All intubated pts & those who w/ significant respiratory distress

Pearls

• Ask about or measure increase above dry body weight as in indication of volume overload

• Look for underlying cause; ask about dietary indiscretion, change in meds



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